Storage Conditions Of Medicinal Gelatin Hollow Capsules

The storage conditions of medicinal gelatin hollow capsules are crucial to ensure their quality, safety, and effectiveness. The following is a detailed introduction to their storage conditions:

1, Temperature control

Recommended storage temperature:

It is usually recommended to store medicinal gelatin hollow capsules in a constant temperature environment of 15 ℃~25 ℃. Excessive temperature can cause the capsule to soften, adhere, or deform; If the temperature is too low, it may make the capsule brittle and increase the risk of rupture.

Temperature fluctuation control:

To avoid severe temperature fluctuations, it is recommended that the temperature fluctuation range of the storage environment does not exceed ± 5 ℃. Temperature fluctuations may cause changes in capsule size, affecting its compatibility with drugs.

2, Humidity control

Recommended relative humidity:

The relative humidity of the storage environment should be controlled between 35% and 65%. Excessive humidity can cause capsules to absorb moisture, expand, soften, and even mold; If the humidity is too low, it may cause the capsule to lose water and become brittle.

Moisture prevention measures:

The storage area should be equipped with dehumidification equipment and avoid contact with water sources or damp items. Capsule packaging should use moisture-proof materials such as aluminum foil bags or sealed cans.

3, Light control

Protect from light:

Medicinal gelatin hollow capsules should avoid direct exposure to sunlight or strong light, as light exposure may cause aging, discoloration, or degradation of the capsule material.

Packaging requirements:

Capsules should be packaged with opaque materials, such as brown glass bottles or opaque aluminum foil bags, to reduce the impact of light exposure.

4, Ventilation and Air Quality

Good ventilation:

The storage area should maintain good ventilation to avoid the accumulation of humidity or odors caused by air retention.

Avoid pollution:

The storage environment should be kept away from chemical substances, volatile organic compounds, or odor sources to prevent capsules from adsorbing odors or undergoing chemical reactions.

5, Packaging and sealing

Sealed packaging:

Capsules should be sealed to prevent external moisture, oxygen, or microbial invasion. After opening, it should be used as soon as possible, and unused capsules should be sealed and stored again.

Anti static treatment:

The packaging material should have anti-static function to prevent capsules from adsorbing dust or sticking to each other due to static electricity.

6, Storage period and inspection

Validity period management:

Medicinal gelatin hollow capsules usually have a clear expiration date and should be used within that period. Expired capsules may undergo physical or chemical changes that can affect drug stability.

Regular inspection:

During storage, the appearance, odor, and physical condition of the capsules should be regularly checked. If adhesion, deformation, discoloration, or odor is found, use should be immediately stopped.

7, Special precautions

Avoid mixing with medication:

Capsules should be stored separately to avoid direct contact with drugs and prevent corrosion or migration of drug components to the capsule material.

Transportation conditions:

During transportation, vehicles with constant temperature and humidity should be used to avoid damage to the capsules caused by high temperature, high humidity, or severe vibration.