Is Gelatin Hollow Capsule Enteric Or Gastric Soluble?

Gelatin hollow capsules can be either gastric soluble or enteric soluble, depending on their preparation process and added excipients. The following is a detailed analysis:

Gastric soluble gelatin hollow capsules

Characteristics: It is easy to disintegrate and release drugs in gastric juice, and compared with tablets and pills, drugs have higher bioavailability.

Applicable situation: Suitable for drugs that have minimal irritation to the gastric mucosa or require rapid release in the stomach.

Advantage:

Protect medication: mask the unpleasant odor of medication and improve patient compliance.

Improve bioavailability: Drugs are quickly released in the stomach for easy absorption.

Wide applicability: can accommodate various powder, liquid, semi-solid, and tablet types.

Enteric coated gelatin hollow capsules

Characteristics: Insoluble in gastric juice, but able to disintegrate in intestinal or colon fluid and release active ingredients.

Applicable situation: Suitable for drugs that are irritating to the gastric mucosa or require release in specific areas of the intestine.

Advantage:

Reduce stomach irritation: The medication is not released in the stomach to avoid irritation to the gastric mucosa.

Precise release: Drugs are released in specific areas of the intestine to improve treatment efficacy.

Controlled release and sustained release: It can achieve timed and targeted release of drugs, reduce the number of times medication is taken, and maintain stable blood drug concentration.

General characteristics of gelatin hollow capsules

Composition: Made from gelatin, water, etc. Gelatin is a water-soluble protein mixture.

Appearance: It is cylindrical in shape and consists of a cap and body that can be fitted and locked together. It is hard and elastic in texture. According to appearance, it can be divided into three types: fully transparent, semi transparent, and opaque, mainly depending on whether they contain light blocking agents.

Safety: Generally not harmful to the human body, but if patients take it for a long time, they may experience gastrointestinal discomfort. People who are allergic to gelatin should not take it.