Is Medicinal Gelatin Hollow Capsule Enteric Or Gastric Soluble?

Medicinal gelatin hollow capsules can be either gastric soluble or enteric soluble, depending on their preparation process and added excipients. The following is a detailed analysis:

Gastric soluble gelatin hollow capsules

Definition and characteristics: Gastric soluble gelatin hollow capsules are ordinary gelatin hollow capsules that have not been specially treated, and their shells are easy to disintegrate and release drugs in gastric juice.

Application scenario: This type of capsule is suitable for situations that require rapid release of drugs in the stomach, such as certain drugs for treating stomach diseases or drugs that require rapid action.

Advantages: Compared with tablets and pills, the drugs in gastric soluble gelatin hollow capsules have higher bioavailability, that is, the utilization of active ingredients is high.

Enteric coated gelatin hollow capsules

Definition and Characteristics: Enteric coated gelatin hollow capsules are gelatin hollow capsules that are processed using special techniques and contain enteric coated materials. Its capsule does not dissolve in gastric juice, but can disintegrate and release active ingredients in intestinal or colon fluid.

Application scenario: This type of capsule is suitable for situations where drugs need to be released in specific parts of the intestine, such as drugs for treating intestinal diseases or drugs that are irritating to the gastric mucosa. Through enteric coating design, it is possible to reduce the stimulation of drugs on the gastric mucosa, while allowing drugs to accurately exert their efficacy at the site of intestinal lesions.

Advantage:

Reduce gastric irritation: Protect the medication from being destroyed by stomach acid in the stomach and reduce the stimulation of the gastric mucosa by the medication.

Precise release: allowing drugs to be released in specific areas of the intestine, improving treatment effectiveness.

Maintaining stable blood drug concentration: widely used in the treatment of various chronic diseases, it can reduce the frequency of medication and maintain stable blood drug concentration.

Selection in practical applications

Select based on drug properties: For drugs that require rapid release in the stomach, choose gastric soluble gelatin hollow capsules; For drugs that need to be released in specific parts of the intestine, choose enteric coated gelatin hollow capsules.

According to the patient's condition selection: For patients with gastrointestinal diseases such as gastric ulcers, enteric coated gelatin hollow capsules can accurately locate the drug release site, reduce the stimulation of the gastric mucosa caused by premature drug release in the stomach, and meet the needs of these patients' conditions.